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Sub-Lethal 5-Fluorouracil Dose Challenges Planarian Stem Cells Promoting Transcriptional Profile Changes in the Pluripotent Sigma-Class Neoblasts

Under physiological conditions, the complex planarian neoblast system is a composite of hierarchically organized stem cell sub-populations with sigma-class neoblasts, including clonogenic neoblasts, endowed with larger self-renewal and differentiation capabilities, thus generating all the other sub-...

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Detalles Bibliográficos
Autores principales: Gambino, Gaetana, Ippolito, Chiara, Evangelista, Monica, Salvetti, Alessandra, Rossi, Leonardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8301986/
https://www.ncbi.nlm.nih.gov/pubmed/34206807
http://dx.doi.org/10.3390/biom11070949