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Sub-Lethal 5-Fluorouracil Dose Challenges Planarian Stem Cells Promoting Transcriptional Profile Changes in the Pluripotent Sigma-Class Neoblasts
Under physiological conditions, the complex planarian neoblast system is a composite of hierarchically organized stem cell sub-populations with sigma-class neoblasts, including clonogenic neoblasts, endowed with larger self-renewal and differentiation capabilities, thus generating all the other sub-...
Autores principales: | Gambino, Gaetana, Ippolito, Chiara, Evangelista, Monica, Salvetti, Alessandra, Rossi, Leonardo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8301986/ https://www.ncbi.nlm.nih.gov/pubmed/34206807 http://dx.doi.org/10.3390/biom11070949 |
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