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Ex Vivo Activation of Red Blood Cell Senescence by Plasma from Sickle-Cell Disease Patients: Correlation between Markers and Adhesion Consequences during Acute Disease Events

BACKGROUND: Blood transfusion remains a key treatment for managing occlusive episodes and painful crises in sickle-cell disease (SCD). In that clinical context, red blood cells (RBCs) from donors and transfused to patients, may be affected by plasma components in the recipients’ blood. Senescence le...

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Detalles Bibliográficos
Autores principales: Chadebech, Philippe, Bodivit, Gwellaouen, Di Liberto, Gaétana, Jouard, Alicia, Vasseur, Corinne, Pirenne, France, Bartolucci, Pablo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8301992/
https://www.ncbi.nlm.nih.gov/pubmed/34208829
http://dx.doi.org/10.3390/biom11070963