Kinetic Constraints in the Specific Interaction between Phosphorylated Ubiquitin and Proteasomal Shuttle Factors

Ubiquitin (Ub) specifically interacts with the Ub-associating domain (UBA) in a proteasomal shuttle factor, while the latter is involved in either proteasomal targeting or self-assembly coacervation. PINK1 phosphorylates Ub at S65 and makes Ub alternate between C-terminally relaxed (pUb(RL)) and ret...

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Detalles Bibliográficos
Autores principales: Qin, Ling-Yun, Gong, Zhou, Liu, Kan, Dong, Xu, Tang, Chun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8301994/
https://www.ncbi.nlm.nih.gov/pubmed/34356632
http://dx.doi.org/10.3390/biom11071008

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8301994/
https://www.ncbi.nlm.nih.gov/pubmed/34356632
http://dx.doi.org/10.3390/biom11071008

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