Celecoxib Analogues for Cancer Treatment: An Update on OSU-03012 and 2,5-Dimethyl-Celecoxib

Cyclooxygenase-2 (COX-2) is an important enzyme involved in prostaglandins biosynthesis from arachidonic acid. COX-2 is frequently overexpressed in human cancers and plays a major tumor promoting function. Accordingly, many efforts have been devoted to efficiently target the catalytic site of this e...

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Detalles Bibliográficos
Autores principales: Sobolewski, Cyril, Legrand, Noémie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8302000/
https://www.ncbi.nlm.nih.gov/pubmed/34356673
http://dx.doi.org/10.3390/biom11071049

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8302000/
https://www.ncbi.nlm.nih.gov/pubmed/34356673
http://dx.doi.org/10.3390/biom11071049

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