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A variable-gain stochastic pooling motif mediates information transfer from receptor assemblies into NF-κB

A myriad of inflammatory cytokines regulate signaling pathways to maintain cellular homeostasis. The IκB kinase (IKK) complex is an integration hub for cytokines that govern nuclear factor κB (NF-κB) signaling. In response to inflammation, IKK is activated through recruitment to receptor-associated...

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Detalles Bibliográficos
Autores principales: Cruz, J. Agustin, Mokashi, Chaitanya S., Kowalczyk, Gabriel J., Guo, Yue, Zhang, Qiuhong, Gupta, Sanjana, Schipper, David L., Smeal, Steven W., Lee, Robin E. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8302133/
https://www.ncbi.nlm.nih.gov/pubmed/34301608
http://dx.doi.org/10.1126/sciadv.abi9410