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Population pharmacokinetics and exposure–response analyses of varenicline in adolescent smokers

Varenicline is an approved smoking cessation aid in adults. Population pharmacokinetics (popPK) and exposure–response (ER) (continuous abstinence rates [CAR] weeks 9‒12 and nausea/vomiting incidence) for varenicline in adolescent smokers were characterized using data from two phase 1 and one phase 4...

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Detalles Bibliográficos
Autores principales: Fediuk, Daryl J., Sweeney, Kevin, Sahasrabudhe, Vaishali, McRae, Thomas, Byon, Wonkyung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8302239/
https://www.ncbi.nlm.nih.gov/pubmed/34062053
http://dx.doi.org/10.1002/psp4.12645