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Pharmacokinetic/pharmacodynamic modeling of drug interactions at the P2Y(12) receptor between selatogrel and oral P2Y(12) antagonists

Selatogrel is a potent and reversible P2Y(12) receptor antagonist developed for subcutaneous self‐administration by patients with suspected acute myocardial infarction. After single‐dose emergency treatment with selatogrel, patients are switched to long‐term treatment with oral P2Y(12) receptor anta...

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Detalles Bibliográficos
Autores principales: Henrich, Andrea, Claussen, Christian Hove, Dingemanse, Jasper, Krause, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8302241/
https://www.ncbi.nlm.nih.gov/pubmed/33955698
http://dx.doi.org/10.1002/psp4.12641