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Lack of N2-gene amplification on the Cepheid Xpert Xpress SARS-CoV-2 assay and potential novel causative mutations: A case series from Auckland, New Zealand

We describe three cases with viral strains that demonstrate impaired N2-gene detection on the Cepheid Xpert Xpress SARS-CoV-2 assay, with two previously undescribed single nucleotide polymorphisms (SNPs): C29197T and G29227T. We propose that these SNPs are likely responsible since they are in close...

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Detalles Bibliográficos
Autores principales: Fox-Lewis, Shivani, Fox-Lewis, Andrew, Harrower, Jay, Chen, Richard, Wang, Jing, de Ligt, Joep, McAuliffe, Gary, Taylor, Susan, Smit, Erasmus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8302484/
https://www.ncbi.nlm.nih.gov/pubmed/34336597
http://dx.doi.org/10.1016/j.idcr.2021.e01233