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Targeting COVID-19 (SARS-CoV-2) main protease through active phytocompounds of ayurvedic medicinal plants – Emblica officinalis (Amla), Phyllanthus niruri Linn. (Bhumi Amla) and Tinospora cordifolia (Giloy) – A molecular docking and simulation study

Coronavirus Disease-2019 (COVID-19), a viral disease caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) was declared a global pandemic by WHO in 2020. In this scenario, SARS-CoV-2 main protease (COVID-19 M(pro)), an enzyme mainly involved in viral replication and transcription is...

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Detalles Bibliográficos
Autores principales: Murugesan, Selvakumar, Kottekad, Sanjay, Crasta, Inchara, Sreevathsan, Sivakumar, Usharani, Dandamudi, Perumal, Madan Kumar, Mudliar, Sandeep Narayan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier Ltd. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8302490/
https://www.ncbi.nlm.nih.gov/pubmed/34329860
http://dx.doi.org/10.1016/j.compbiomed.2021.104683