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Atomistic Basis of Microtubule Dynamic Instability Assessed Via Multiscale Modeling
Microtubule “dynamic instability,” the abrupt switching from assembly to disassembly caused by the hydrolysis of GTP to GDP within the β subunit of the αβ-tubulin heterodimer, is necessary for vital cellular processes such as mitosis and migration. Despite existing high-resolution structural data, t...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Springer International Publishing
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8302526/ https://www.ncbi.nlm.nih.gov/pubmed/33537926 http://dx.doi.org/10.1007/s10439-020-02715-6 |