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Atomistic Basis of Microtubule Dynamic Instability Assessed Via Multiscale Modeling

Microtubule “dynamic instability,” the abrupt switching from assembly to disassembly caused by the hydrolysis of GTP to GDP within the β subunit of the αβ-tubulin heterodimer, is necessary for vital cellular processes such as mitosis and migration. Despite existing high-resolution structural data, t...

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Detalles Bibliográficos
Autores principales:	Hemmat, Mahya, Odde, David J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer International Publishing 2021
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8302526/ https://www.ncbi.nlm.nih.gov/pubmed/33537926 http://dx.doi.org/10.1007/s10439-020-02715-6

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