Neutralization of the induced VEGF-A potentiates the therapeutic effect of an anti-VEGFR2 antibody on gastric cancer in vivo

The vascular endothelial growth factor (VEGF)/VEGF receptor (VEGFR) axis is an essential regulator of angiogenesis and important therapeutic target in cancer. Ramucirumab is an anti-VEGFR2 monoclonal antibody used for the treatment of several cancers. Increased circulating VEGF-A levels after ramuci...

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Detalles Bibliográficos
Autores principales: Mashima, Tetsuo, Wakatsuki, Takeru, Kawata, Naomi, Jang, Myung-Kyu, Nagamori, Akiko, Yoshida, Haruka, Nakamura, Kenichi, Migita, Toshiro, Seimiya, Hiroyuki, Yamaguchi, Kensei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8302577/
https://www.ncbi.nlm.nih.gov/pubmed/34302038
http://dx.doi.org/10.1038/s41598-021-94584-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8302577/
https://www.ncbi.nlm.nih.gov/pubmed/34302038
http://dx.doi.org/10.1038/s41598-021-94584-9

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