Quantitative imaging of transcription in living Drosophila embryos reveals the impact of core promoter motifs on promoter state dynamics

Genes are expressed in stochastic transcriptional bursts linked to alternating active and inactive promoter states. A major challenge in transcription is understanding how promoter composition dictates bursting, particularly in multicellular organisms. We investigate two key Drosophila developmental...

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Detalles Bibliográficos
Autores principales: Pimmett, Virginia L., Dejean, Matthieu, Fernandez, Carola, Trullo, Antonio, Bertrand, Edouard, Radulescu, Ovidiu, Lagha, Mounia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8302612/
https://www.ncbi.nlm.nih.gov/pubmed/34301936
http://dx.doi.org/10.1038/s41467-021-24461-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8302612/
https://www.ncbi.nlm.nih.gov/pubmed/34301936
http://dx.doi.org/10.1038/s41467-021-24461-6

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