The role of IL-1 in adipose browning and muscle wasting in CKD-associated cachexia

Cytokines such as IL-6, TNF-α and IL-1β trigger inflammatory cascades which may play a role in the pathogenesis of chronic kidney disease (CKD)-associated cachexia. CKD was induced by 5/6 nephrectomy in mice. We studied energy homeostasis in Il1β(−/−)/CKD, Il6(−/−)/CKD and Tnfα(−/−)/CKD mice and com...

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Detalles Bibliográficos
Autores principales: Cheung, Wai W., Zheng, Ronghao, Hao, Sheng, Wang, Zhen, Gonzalez, Alex, Zhou, Ping, Hoffman, Hal M., Mak, Robert H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8302616/
https://www.ncbi.nlm.nih.gov/pubmed/34302016
http://dx.doi.org/10.1038/s41598-021-94565-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8302616/
https://www.ncbi.nlm.nih.gov/pubmed/34302016
http://dx.doi.org/10.1038/s41598-021-94565-y

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