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The role of IL-1 in adipose browning and muscle wasting in CKD-associated cachexia
Cytokines such as IL-6, TNF-α and IL-1β trigger inflammatory cascades which may play a role in the pathogenesis of chronic kidney disease (CKD)-associated cachexia. CKD was induced by 5/6 nephrectomy in mice. We studied energy homeostasis in Il1β(−/−)/CKD, Il6(−/−)/CKD and Tnfα(−/−)/CKD mice and com...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8302616/ https://www.ncbi.nlm.nih.gov/pubmed/34302016 http://dx.doi.org/10.1038/s41598-021-94565-y |