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Heterogeneous effects of genetic risk for Alzheimer’s disease on the phenome
Here we report how four major forms of Alzheimer’s disease (AD) genetic risk—APOE-ε4, APOE-ε2, polygenic risk and familial risk—are associated with 273 traits in ~500,000 individuals in the UK Biobank. The traits cover blood biochemistry and cell traits, metabolic and general health, psychosocial he...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8302633/ https://www.ncbi.nlm.nih.gov/pubmed/34301914 http://dx.doi.org/10.1038/s41398-021-01518-0 |