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Heterogeneous effects of genetic risk for Alzheimer’s disease on the phenome

Here we report how four major forms of Alzheimer’s disease (AD) genetic risk—APOE-ε4, APOE-ε2, polygenic risk and familial risk—are associated with 273 traits in ~500,000 individuals in the UK Biobank. The traits cover blood biochemistry and cell traits, metabolic and general health, psychosocial he...

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Detalles Bibliográficos
Autores principales:	Wu, Hei Man, Goate, Alison M., O’Reilly, Paul F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8302633/ https://www.ncbi.nlm.nih.gov/pubmed/34301914 http://dx.doi.org/10.1038/s41398-021-01518-0

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