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Adenosine deaminase modulates metabolic remodeling and orchestrates joint destruction in rheumatoid arthritis
Rheumatoid Arthritis (RA) is a chronic autoimmune disease associated with inflammation and joint remodeling. Adenosine deaminase (ADA), a risk factor in RA, degrades adenosine, an anti-inflammatory molecule, resulting in an inflammatory bias. We present an integrative analysis of clinical data, cyto...
Autores principales: | , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8302689/ https://www.ncbi.nlm.nih.gov/pubmed/34301999 http://dx.doi.org/10.1038/s41598-021-94607-5 |