Adenosine deaminase modulates metabolic remodeling and orchestrates joint destruction in rheumatoid arthritis

Rheumatoid Arthritis (RA) is a chronic autoimmune disease associated with inflammation and joint remodeling. Adenosine deaminase (ADA), a risk factor in RA, degrades adenosine, an anti-inflammatory molecule, resulting in an inflammatory bias. We present an integrative analysis of clinical data, cyto...

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Detalles Bibliográficos
Autores principales: Bhagavatham, Sai Krishna Srimadh, Khanchandani, Prakash, Kannan, Vishnu, Potikuri, Damodaram, Sridharan, Divya, Pulukool, Sujith Kumar, Naik, Ashwin Ashok, Dandamudi, Rajesh Babu, Divi, Sai Mangala, Pargaonkar, Ashish, Ray, Rahul, Santha, Saibharath Simha Reddy, Seshagiri, Polani B., Narasimhan, K., Gumdal, Narsimulu, Sivaramakrishnan, Venketesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8302689/
https://www.ncbi.nlm.nih.gov/pubmed/34301999
http://dx.doi.org/10.1038/s41598-021-94607-5

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