A connexin/ifi30 pathway bridges HSCs with their niche to dampen oxidative stress

Reactive oxygen species (ROS) represent a by-product of metabolism and their excess is toxic for hematopoietic stem and progenitor cells (HSPCs). During embryogenesis, a small number of HSPCs are produced from the hemogenic endothelium, before they colonize a transient organ where they expand, for e...

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Detalles Bibliográficos
Autores principales: Cacialli, Pietro, Mahony, Christopher B., Petzold, Tim, Bordignon, Patrizia, Rougemont, Anne-Laure, Bertrand, Julien Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8302694/
https://www.ncbi.nlm.nih.gov/pubmed/34301940
http://dx.doi.org/10.1038/s41467-021-24831-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8302694/
https://www.ncbi.nlm.nih.gov/pubmed/34301940
http://dx.doi.org/10.1038/s41467-021-24831-0

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