Spatio-temporal biodistribution of (89)Zr-oxine labeled huLym-1-A-BB3z-CAR T-cells by PET imaging in a preclinical tumor model

Quantitative in vivo monitoring of cell biodistribution offers assessment of treatment efficacy in real-time and can provide guidance for further optimization of chimeric antigen receptor (CAR) modified cell therapy. We evaluated the utility of a non-invasive, serial (89)Zr-oxine PET imaging to asse...

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Detalles Bibliográficos
Autores principales: Sta Maria, Naomi S., Khawli, Leslie A., Pachipulusu, Vyshnavi, Lin, Sharon W., Zheng, Long, Cohrs, Daniel, Liu, Xiaodan, Hu, Peisheng, Epstein, Alan L., Jacobs, Russell E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8302724/
https://www.ncbi.nlm.nih.gov/pubmed/34302002
http://dx.doi.org/10.1038/s41598-021-94490-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8302724/
https://www.ncbi.nlm.nih.gov/pubmed/34302002
http://dx.doi.org/10.1038/s41598-021-94490-0

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