Rational construction of genome-reduced Burkholderiales chassis facilitates efficient heterologous production of natural products from proteobacteria

Heterologous expression of biosynthetic gene clusters (BGCs) avails yield improvements and mining of natural products, but it is limited by lacking of more efficient Gram-negative chassis. The proteobacterium Schlegelella brevitalea DSM 7029 exhibits potential for heterologous BGC expression, but it...

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Detalles Bibliográficos
Autores principales: Liu, Jiaqi, Zhou, Haibo, Yang, Zhiyu, Wang, Xue, Chen, Hanna, Zhong, Lin, Zheng, Wentao, Niu, Weijing, Wang, Sen, Ren, Xiangmei, Zhong, Guannan, Wang, Yan, Ding, Xiaoming, Müller, Rolf, Zhang, Youming, Bian, Xiaoying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8302735/
https://www.ncbi.nlm.nih.gov/pubmed/34301933
http://dx.doi.org/10.1038/s41467-021-24645-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8302735/
https://www.ncbi.nlm.nih.gov/pubmed/34301933
http://dx.doi.org/10.1038/s41467-021-24645-0

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