RNase κ promotes robust piRNA production by generating 2′,3′-cyclic phosphate-containing precursors

In animal germlines, PIWI proteins and the associated PIWI-interacting RNAs (piRNAs) protect genome integrity by silencing transposons. Here we report the extensive sequence and quantitative correlations between 2′,3′-cyclic phosphate-containing RNAs (cP-RNAs), identified using cP-RNA-seq, and piRNA...

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Detalles Bibliográficos
Autores principales: Shigematsu, Megumi, Kawamura, Takuya, Morichika, Keisuke, Izumi, Natsuko, Kiuchi, Takashi, Honda, Shozo, Pliatsika, Venetia, Matsubara, Ryuma, Rigoutsos, Isidore, Katsuma, Susumu, Tomari, Yukihide, Kirino, Yohei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8302750/
https://www.ncbi.nlm.nih.gov/pubmed/34301931
http://dx.doi.org/10.1038/s41467-021-24681-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8302750/
https://www.ncbi.nlm.nih.gov/pubmed/34301931
http://dx.doi.org/10.1038/s41467-021-24681-w

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