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Genetic architecture of type 1 diabetes with low genetic risk score informed by 41 unreported loci

Type 1 diabetes (T1D) patients with low genetic risk scores (GRS) may be non-autoimmune or autoimmune mediated by other genetic loci. The T1D-GRS2 provides us an opportunity to look into the genetic architecture of these patients. A total of 18,949 European individuals were included in this study, i...

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Detalles Bibliográficos
Autores principales: Qu, Hui-Qi, Qu, Jingchun, Bradfield, Jonathan, Marchand, Luc, Glessner, Joseph, Chang, Xiao, March, Michael, Li, Jin, Connolly, John J., Roizen, Jeffrey D., Sleiman, Patrick, Polychronakos, Constantin, Hakonarson, Hakon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8302754/
https://www.ncbi.nlm.nih.gov/pubmed/34302048
http://dx.doi.org/10.1038/s42003-021-02368-8