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Silencing the G-protein coupled receptor 3-salt inducible kinase 2 pathway promotes human β cell proliferation

Loss of pancreatic β cells is the hallmark of type 1 diabetes, for which provision of insulin is the standard of care. While regenerative and stem cell therapies hold the promise of generating single-source or host-matched tissue to obviate immune-mediated complications, these will still require sur...

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Detalles Bibliográficos
Autores principales: Iorio, Caterina, Rourke, Jillian L., Wells, Lisa, Sakamaki, Jun-Ichi, Moon, Emily, Hu, Queenie, Kin, Tatsuya, Screaton, Robert A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8302759/
https://www.ncbi.nlm.nih.gov/pubmed/34302056
http://dx.doi.org/10.1038/s42003-021-02433-2