A multi-step nucleation process determines the kinetics of prion-like domain phase separation

Compartmentalization by liquid-liquid phase separation (LLPS) has emerged as a ubiquitous mechanism underlying the organization of biomolecules in space and time. Here, we combine rapid-mixing time-resolved small-angle X-ray scattering (SAXS) approaches to characterize the assembly kinetics of a pro...

Descripción completa

Detalles Bibliográficos
Autores principales: Martin, Erik W., Harmon, Tyler S., Hopkins, Jesse B., Chakravarthy, Srinivas, Incicco, J. Jeremías, Schuck, Peter, Soranno, Andrea, Mittag, Tanja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8302766/
https://www.ncbi.nlm.nih.gov/pubmed/34301955
http://dx.doi.org/10.1038/s41467-021-24727-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8302766/
https://www.ncbi.nlm.nih.gov/pubmed/34301955
http://dx.doi.org/10.1038/s41467-021-24727-z

Ejemplares similares