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A multi-step nucleation process determines the kinetics of prion-like domain phase separation

Compartmentalization by liquid-liquid phase separation (LLPS) has emerged as a ubiquitous mechanism underlying the organization of biomolecules in space and time. Here, we combine rapid-mixing time-resolved small-angle X-ray scattering (SAXS) approaches to characterize the assembly kinetics of a pro...

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Detalles Bibliográficos
Autores principales:	Martin, Erik W., Harmon, Tyler S., Hopkins, Jesse B., Chakravarthy, Srinivas, Incicco, J. Jeremías, Schuck, Peter, Soranno, Andrea, Mittag, Tanja
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8302766/ https://www.ncbi.nlm.nih.gov/pubmed/34301955 http://dx.doi.org/10.1038/s41467-021-24727-z

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