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Inhibition of the Combinatorial Signaling of Transforming Growth Factor-Beta and NOTCH Promotes Myotube Formation of Human Pluripotent Stem Cell-Derived Skeletal Muscle Progenitor Cells

Understanding the signaling pathways that regulate the final differentiation of human myoblasts is essential for successful cell transplantation and drug screening for the treatment of muscular dystrophy. In an effort to improve myotube formation from hiPSC-derived myoblasts, we validated a collecti...

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Detalles Bibliográficos
Autores principales: Choi, In Young, Lim, Ho Tae, Che, Young Hyun, Lee, Gabsang, Kim, Yong Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8303216/
https://www.ncbi.nlm.nih.gov/pubmed/34209364
http://dx.doi.org/10.3390/cells10071649