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Btk Inhibitors: A Medicinal Chemistry and Drug Delivery Perspective

In the past few years, Bruton’s tyrosine Kinase (Btk) has emerged as new target in medicinal chemistry. Since approval of ibrutinib in 2013 for treatment of different hematological cancers (as leukemias and lymphomas), two other irreversible Btk inhibitors have been launched on the market. In the at...

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Detalles Bibliográficos
Autores principales: Brullo, Chiara, Villa, Carla, Tasso, Bruno, Russo, Eleonora, Spallarossa, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8303217/
https://www.ncbi.nlm.nih.gov/pubmed/34299259
http://dx.doi.org/10.3390/ijms22147641