Exploiting DNA Damage Repair in Precision Cancer Therapy: BRCA1 as a Prime Therapeutic Target

SIMPLE SUMMARY: Chemical inhibition of central DNA damage repair (DDR) proteins has become a promising approach in precision cancer therapy. In particular, BRCA1 and its DDR-associated proteins constitute important targets for developing DNA repair inhibiting drugs. This review provides relevant ins...

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Detalles Bibliográficos
Autores principales: Raimundo, Liliana, Calheiros, Juliana, Saraiva, Lucília
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8303227/
https://www.ncbi.nlm.nih.gov/pubmed/34298653
http://dx.doi.org/10.3390/cancers13143438

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8303227/
https://www.ncbi.nlm.nih.gov/pubmed/34298653
http://dx.doi.org/10.3390/cancers13143438

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