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Exploiting DNA Damage Repair in Precision Cancer Therapy: BRCA1 as a Prime Therapeutic Target

SIMPLE SUMMARY: Chemical inhibition of central DNA damage repair (DDR) proteins has become a promising approach in precision cancer therapy. In particular, BRCA1 and its DDR-associated proteins constitute important targets for developing DNA repair inhibiting drugs. This review provides relevant ins...

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Detalles Bibliográficos
Autores principales:	Raimundo, Liliana, Calheiros, Juliana, Saraiva, Lucília
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8303227/ https://www.ncbi.nlm.nih.gov/pubmed/34298653 http://dx.doi.org/10.3390/cancers13143438

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