Controlled Release of 18-β-Glycyrrhetinic Acid from Core-Shell Nanoparticles: Effects on Cytotoxicity and Intracellular Concentration in HepG2 Cell Line

18β-glycyrrhetinic acid (GA) is a pentacyclic triterpene with promising hepatoprotective and anti-Hepatocellular carcinoma effects. GA low water solubility however reduces its biodistribution and bioavailability, limiting its applications in biomedicine. In this work we used core-shell NPs made of P...

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Detalles Bibliográficos
Autores principales: Nocca, Giuseppina, D’Avenio, Giuseppe, Amalfitano, Adriana, Chronopoulou, Laura, Mordente, Alvaro, Palocci, Cleofe, Grigioni, Mauro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8303372/
https://www.ncbi.nlm.nih.gov/pubmed/34300811
http://dx.doi.org/10.3390/ma14143893

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8303372/
https://www.ncbi.nlm.nih.gov/pubmed/34300811
http://dx.doi.org/10.3390/ma14143893

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