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Differential but Concerted Expression of HSD17B2, HSD17B3, SHBG and SRD5A1 Testosterone Tetrad Modulate Therapy Response and Susceptibility to Disease Relapse in Patients with Prostate Cancer

SIMPLE SUMMARY: Over the last two decades, our improved understanding of the pathobiology of androgen-addicted prostate cancer (PCa), and documented therapeutic advances/breakthroughs have not translated into any substantial or sustained curative benefit for patients treated with traditional ADT or...

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Detalles Bibliográficos
Autores principales: Bamodu, Oluwaseun Adebayo, Tzou, Kai-Yi, Lin, Chia-Da, Hu, Su-Wei, Wang, Yuan-Hung, Wu, Wen-Ling, Chen, Kuan-Chou, Wu, Chia-Chang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8303483/
https://www.ncbi.nlm.nih.gov/pubmed/34298692
http://dx.doi.org/10.3390/cancers13143478