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Antiproliferative Properties and G-Quadruplex-Binding of Symmetrical Naphtho[1,2-b:8,7-b’]dithiophene Derivatives

Background: G-quadruplex (G4) forming sequences are recurrent in telomeres and promoter regions of several protooncogenes. In normal cells, the transient arrangements of DNA in G-tetrads may regulate replication, transcription, and translation processes. Tumors are characterized by uncontrolled cell...

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Detalles Bibliográficos
Autores principales: Lauria, Antonino, La Monica, Gabriele, Terenzi, Alessio, Mannino, Giuseppe, Bonsignore, Riccardo, Bono, Alessia, Almerico, Anna Maria, Barone, Giampaolo, Gentile, Carla, Martorana, Annamaria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8303715/
https://www.ncbi.nlm.nih.gov/pubmed/34299583
http://dx.doi.org/10.3390/molecules26144309