Cargando…

Antiproliferative Properties and G-Quadruplex-Binding of Symmetrical Naphtho[1,2-b:8,7-b’]dithiophene Derivatives

Background: G-quadruplex (G4) forming sequences are recurrent in telomeres and promoter regions of several protooncogenes. In normal cells, the transient arrangements of DNA in G-tetrads may regulate replication, transcription, and translation processes. Tumors are characterized by uncontrolled cell...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lauria, Antonino, La Monica, Gabriele, Terenzi, Alessio, Mannino, Giuseppe, Bonsignore, Riccardo, Bono, Alessia, Almerico, Anna Maria, Barone, Giampaolo, Gentile, Carla, Martorana, Annamaria
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8303715/ https://www.ncbi.nlm.nih.gov/pubmed/34299583 http://dx.doi.org/10.3390/molecules26144309

Ejemplares similares

N,N′-Bis(2-cyclohexylethyl)naphtho[2,3-b:6,7-b′]dithiophene Diimides: Effects of Substituents
por: Nakano, Masahiro, et al.
Publicado: (2016)

Antiproliferative Activity Predictor: A New Reliable In Silico Tool for Drug Response Prediction against NCI60 Panel
por: Martorana, Annamaria, et al.
Publicado: (2022)

Nonfullerene Near-Infrared Sensitive Acceptors “Octacyclic Naphtho[1,2-b:5,6-b] Dithiophene Core” for Organic Solar Cell Applications: In Silico Molecular Engineering
por: Sattar, Abdul, et al.
Publicado: (2022)

Design and Synthesis of Novel Thieno[3,2-c]quinoline Compounds with Antiproliferative Activity on RET-Dependent Medullary Thyroid Cancer Cells
por: La Monica, Gabriele, et al.
Publicado: (2023)

In Silico Identification of Small Molecules as New Cdc25 Inhibitors through the Correlation between Chemosensitivity and Protein Expression Pattern
por: Lauria, Antonino, et al.
Publicado: (2021)

Benzo[1,2-b:4,5-b′]dithiophene-4,8-dione
por: Ramirez, Amanda L., et al.
Publicado: (2012)

G‐Quadruplex Recognition by DARPIns through Epitope/Paratope Analogy
por: Miclot, Tom, et al.
Publicado: (2022)

Facile dione protection to benzo[1,2-b:6,5-b’]dithiophene-4,5-dione (BDTD) in triggering ultraviolet emission – A new member of the emissive 3,3′-bridged dithiophenes
por: Li, Chengpeng, et al.
Publicado: (2023)

Transistor Properties of 2,7-Dialkyl-Substituted Phenanthro[2,1-b:7,8-b′]dithiophene
por: Kubozono, Yoshihiro, et al.
Publicado: (2016)

Synthesis and Physicochemical Properties of 2,7-Disubstituted Phenanthro[2,1-b:7,8-b’]dithiophenes
por: Ji, Zhenfei, et al.
Publicado: (2020)

In Silico Insights into the SARS CoV-2 Main Protease Suggest NADH Endogenous Defences in the Control of the Pandemic Coronavirus Infection
por: Martorana, Annamaria, et al.
Publicado: (2020)

Phytochemical Profile and Antioxidant, Antiproliferative, and Antimicrobial Properties of Rubus idaeus Seed Powder
por: Mannino, Giuseppe, et al.
Publicado: (2022)

Off-Target-Based Design of Selective HIV-1 PROTEASE Inhibitors
por: Monica, Gabriele La, et al.
Publicado: (2021)

Targeting SARS-CoV-2 Main Protease for Treatment of COVID-19: Covalent Inhibitors Structure–Activity Relationship Insights and Evolution Perspectives
por: La Monica, Gabriele, et al.
Publicado: (2022)

Never Cared for What They Do: High Structural Stability of Guanine-Quadruplexes in the Presence of Strand-Break Damage
por: Miclot, Tom, et al.
Publicado: (2022)

Synthesis and Physicochemical Properties of Piceno[4,3-b:9,10-b′]dithiophene Derivatives and Their Application in Organic Field-Effect Transistors
por: Hyodo, Keita, et al.
Publicado: (2017)

New Non-Fullerene Acceptor with Extended Conjugation of Cyclopenta [2,1-b:3,4-b’] Dithiophene for Organic Solar Cells
por: Sun, Cheng, et al.
Publicado: (2022)

In Silico Mixed Ligand/Structure-Based Design of New CDK-1/PARP-1 Dual Inhibitors as Anti-Breast Cancer Agents
por: Bono, Alessia, et al.
Publicado: (2023)

Resolving a guanine-quadruplex structure in the SARS-CoV-2 genome through circular dichroism and multiscale molecular modeling
por: D'Anna, Luisa, et al.
Publicado: (2023)

Targeting G-quadruplexes with Organic Dyes: Chelerythrine–DNA Binding Elucidated by Combining Molecular Modeling and Optical Spectroscopy
por: Terenzi, Alessio, et al.
Publicado: (2019)

Bimodular Antiparallel G-Quadruplex Nanoconstruct with Antiproliferative Activity
por: Antipova, Olga, et al.
Publicado: (2019)

Growth Dynamics of Ultrathin Films of Benzo[1,2-b:4,5-b’]dithiophene Derivatives on Au(111): A Photoelectron Spectroscopy Investigation
por: Stummo, Angelo, et al.
Publicado: (2023)

How the Metal Ion Affects the (1)H NMR Chemical Shift Values of Schiff Base Metal Complexes: Rationalization by DFT Calculations
por: Butera, Valeria, et al.
Publicado: (2023)

In Silico Design of New Dual Inhibitors of SARS-CoV-2 M(PRO) through Ligand- and Structure-Based Methods
por: Bono, Alessia, et al.
Publicado: (2023)

6-Phenylbenzo[d]naphtho[2,3-b]thiophene
por: Silambarasan, V., et al.
Publicado: (2012)

Disordering of Human Telomeric G-Quadruplex with Novel Antiproliferative Anthrathiophenedione
por: Kaluzhny, Dmitry, et al.
Publicado: (2011)

Side-chain Engineering of Benzo[1,2-b:4,5-b’]dithiophene Core-structured Small Molecules for High-Performance Organic Solar Cells
por: Yin, Xinxing, et al.
Publicado: (2016)

Molecular Ordering of Dithieno[2,3-d;2′,3′-d]benzo[2,1-b:3,4-b′]dithiophenes for Field-Effect Transistors
por: Keerthi, Ashok, et al.
Publicado: (2018)

Dithiophene‐Fused Oxadiborepins and Azadiborepins: A New Class of Highly Fluorescent Heteroaromatics
por: Crumbach, Merian, et al.
Publicado: (2021)

2-Methyl-3-(phenylsulfonyl)naphtho[1,2-b]furan
por: Choi, Hong Dae, et al.
Publicado: (2008)

N-(Phenylsulfonyl)naphtho[2,1-b]furan-1-carboxamide
por: Shetprakash, M., et al.
Publicado: (2011)

2-Phenyl-1-(phenylsulfinyl)naphtho[2,1-b]furan
por: Choi, Hong Dae, et al.
Publicado: (2009)

2-Methyl-1-(phenylsulfonyl)naphtho[2,1-b]furan
por: Choi, Hong Dae, et al.
Publicado: (2008)

7-Bromo-2-methyl-1-tosylnaphtho[2,1-b]furan
por: Choi, Hong Dae, et al.
Publicado: (2008)

2-Phenyl-3-(phenylsulfinyl)naphtho[1,2-b]furan
por: Choi, Hong Dae, et al.
Publicado: (2009)

1-Cyclohexylsulfinyl-2-methylnaphtho[2,1-b]furan
por: Choi, Hong Dae, et al.
Publicado: (2011)

Ethyl 5-bromonaphtho[2,1-b]furan-2-carboxylate
por: Shet Prakash, M., et al.
Publicado: (2013)

The efficient synthesis of dibenzo[d,d′]benzo[1,2-b:4,3-b′]dithiophene and cyclopenta[1,2-b:4,3-b′]bis(benzo[d]thiophen)-6-one
por: Wang, Zhihua, et al.
Publicado: (2009)

Another step toward DNA selective targeting: Ni(II) and Cu(II) complexes of a Schiff base ligand able to bind gene promoter G-quadruplexes
por: Terenzi, Alessio, et al.
Publicado: (2016)

12-Benzoyl-2-methylnaphtho[2,3-b]indolizine-6,11-dione
por: Liu, Yun, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_tbkat3nomrau9j2a8j332gbcvb