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Anti-Inflammatory Effect of Very High Dose Local Vessel Wall Statin Administration: Poly(L,L-Lactide) Biodegradable Microspheres with Simvastatin for Drug Delivery System (DDS)

Atherosclerosis involves an ongoing inflammatory response of the vascular endothelium and vessel wall of the aorta and vein. The pleiotropic effects of statins have been well described in many in vitro and in vivo studies, but these effects are difficult to achieve in clinical practice due to the lo...

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Detalles Bibliográficos
Autores principales: Wacinski, Piotr, Gadzinowski, Mariusz, Dabrowski, Wojciech, Szumilo, Justyna, Wacinski, Jakub, Oru, Nathalie, Vicaut, Eric, Czuczwar, Stanislaw, Kocki, Janusz, Basinska, Teresa, Slomkowski, Stanislaw
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8303821/
https://www.ncbi.nlm.nih.gov/pubmed/34299106
http://dx.doi.org/10.3390/ijms22147486