The Role of Autophagy in Chemical Proteasome Inhibition Model of Retinal Degeneration

We recently demonstrated that chemical proteasome inhibition induced inner retinal degeneration, supporting the pivotal roles of the ubiquitin–proteasome system in retinal structural integrity maintenance. In this study, using beclin1-heterozygous (Becn1-Het) mice with autophagic dysfunction, we tes...

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Detalles Bibliográficos
Autores principales: Gunawan, Merry, Low, Choonbing, Neo, Kurt, Yeo, Siawey, Ho, Candice, Barathi, Veluchamy A., Chan, Anita Sookyee, Sharif, Najam A., Kageyama, Masaaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8303873/
https://www.ncbi.nlm.nih.gov/pubmed/34298888
http://dx.doi.org/10.3390/ijms22147271

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8303873/
https://www.ncbi.nlm.nih.gov/pubmed/34298888
http://dx.doi.org/10.3390/ijms22147271

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