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The Role of Autophagy in Chemical Proteasome Inhibition Model of Retinal Degeneration
We recently demonstrated that chemical proteasome inhibition induced inner retinal degeneration, supporting the pivotal roles of the ubiquitin–proteasome system in retinal structural integrity maintenance. In this study, using beclin1-heterozygous (Becn1-Het) mice with autophagic dysfunction, we tes...
Autores principales: | Gunawan, Merry, Low, Choonbing, Neo, Kurt, Yeo, Siawey, Ho, Candice, Barathi, Veluchamy A., Chan, Anita Sookyee, Sharif, Najam A., Kageyama, Masaaki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8303873/ https://www.ncbi.nlm.nih.gov/pubmed/34298888 http://dx.doi.org/10.3390/ijms22147271 |
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