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Comparing Tumor Cell Invasion and Myeloid Cell Composition in Compatible Primary and Relapsing Glioblastoma

SIMPLE SUMMARY: We established a new minimally invasive mouse model for GBM relapse. For this, we utilized orthotopical implantation of HSVTK-transduced GBM cells and pharmacological treatment with GCV. In addition, we implanted patient-derived GBM cells of primary or recurrent tumors. We found that...

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Detalles Bibliográficos
Autores principales: Zhao, Dongxu, Zhang, Huabin, Uyar, Ramazan, Hossain, Jubayer A., Miletic, Hrvoje, Tonn, Jörg-Christian, Glass, Rainer, Kälin, Roland E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8303884/
https://www.ncbi.nlm.nih.gov/pubmed/34298846
http://dx.doi.org/10.3390/cancers13143636