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Hypoxia Enhances the Expression of RNASET2 in Human Monocyte-Derived Dendritic Cells: Role of PI3K/AKT Pathway

Hypoxia is a key component of the tumor microenvironment (TME) and promotes not only tumor growth and metastasis, but also negatively affects infiltrating immune cells by impairing host immunity. Dendritic cells (DCs) are the most potent antigen-presenting cells and their biology is weakened in the...

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Detalles Bibliográficos
Autores principales: Monaci, Sara, Coppola, Federica, Giuntini, Gaia, Roncoroni, Rossella, Acquati, Francesco, Sozzani, Silvano, Carraro, Fabio, Naldini, Antonella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8303897/
https://www.ncbi.nlm.nih.gov/pubmed/34299186
http://dx.doi.org/10.3390/ijms22147564