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Silencing of HMGA2 by siRNA Loaded Methotrexate Functionalized Polyamidoamine Dendrimer for Human Breast Cancer Cell Therapy

The transcription factor high mobility group protein A2 (HMGA2) plays an important role in the pathogenesis of some cancers including breast cancer. Polyamidoamine dendrimer generation 4 is a kind of highly branched polymeric nanoparticle with surface charge and highest density peripheral groups tha...

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Detalles Bibliográficos
Autores principales: Abedi Gaballu, Fereydoon, Cho, William Chi-Shing, Dehghan, Gholamreza, Zarebkohan, Amir, Baradaran, Behzad, Mansoori, Behzad, Abbaspour-Ravasjani, Soheil, Mohammadi, Ali, Sheibani, Nader, Aghanejad, Ayuob, Ezzati Nazhad Dolatabadi, Jafar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8303903/
https://www.ncbi.nlm.nih.gov/pubmed/34356120
http://dx.doi.org/10.3390/genes12071102