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Influence of CYP2C9 Genetic Polymorphisms on the Pharmacokinetics of Losartan and Its Active Metabolite E-3174: A Systematic Review and Meta-Analysis

This study aimed to investigate the influence of CYP2C9 genetic polymorphisms on the pharmacokinetics of losartan and its active metabolite, E-3174, through a systematic review and meta-analysis. Eight studies published before March 2021 were included in this study. We used PubMed, the Cochrane Libr...

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Detalles Bibliográficos
Autores principales: Park, Yoon-A, Song, Yu-bin, Yee, Jeong, Yoon, Ha-Young, Gwak, Hye-Sun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8303964/
https://www.ncbi.nlm.nih.gov/pubmed/34210056
http://dx.doi.org/10.3390/jpm11070617