Differences in Ovarian and Other Cancers Risks by Population and BRCA Mutation Location

Hereditary breast and ovarian cancer is caused by a germline mutation in BRCA1 or BRCA2 genes. The frequency of germline BRCA1/2 gene mutation carriers and the ratio of germline BRCA1 to BRCA2 mutations in BRCA-related cancer patients vary depending on the population. Genotype and phenotype correlat...

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Detalles Bibliográficos
Autores principales: Sekine, Masayuki, Nishino, Koji, Enomoto, Takayuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8303997/
https://www.ncbi.nlm.nih.gov/pubmed/34356066
http://dx.doi.org/10.3390/genes12071050

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8303997/
https://www.ncbi.nlm.nih.gov/pubmed/34356066
http://dx.doi.org/10.3390/genes12071050

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