Double Proton Tautomerism via Intra- or Intermolecular Pathways? The Case of Tetramethyl Reductic Acid Studied by Dynamic NMR: Hydrogen Bond Association, Solvent and Kinetic H/D Isotope Effects

Using dynamic liquid-state NMR spectroscopy a degenerate double proton tautomerism was detected in tetramethyl reductic acid (TMRA) dissolved in toluene-d(8) and in CD(2)Cl(2). Similar to vitamin C, TMRA belongs to the class of reductones of biologically important compounds. The tautomerism involves...

Descripción completa

Detalles Bibliográficos
Autores principales: Limbach, Hans-Heinrich, Baumgärtner, Simone, Franke, Roland, Männle, Ferdinand, Scherer, Gerd, Denisov, Gleb S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8304075/
https://www.ncbi.nlm.nih.gov/pubmed/34299648
http://dx.doi.org/10.3390/molecules26144373

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8304075/
https://www.ncbi.nlm.nih.gov/pubmed/34299648
http://dx.doi.org/10.3390/molecules26144373

Ejemplares similares