A Concerted Action of UBA5 C-Terminal Unstructured Regions Is Important for Transfer of Activated UFM1 to UFC1

Ubiquitin fold modifier 1 (UFM1) is a member of the ubiquitin-like protein family. UFM1 undergoes a cascade of enzymatic reactions including activation by UBA5 (E1), transfer to UFC1 (E2) and selective conjugation to a number of target proteins via UFL1 (E3) enzymes. Despite the importance of ufmyla...

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Detalles Bibliográficos
Autores principales: Wesch, Nicole, Löhr, Frank, Rogova, Natalia, Dötsch, Volker, Rogov, Vladimir V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8304084/
https://www.ncbi.nlm.nih.gov/pubmed/34299007
http://dx.doi.org/10.3390/ijms22147390

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8304084/
https://www.ncbi.nlm.nih.gov/pubmed/34299007
http://dx.doi.org/10.3390/ijms22147390

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