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A Concerted Action of UBA5 C-Terminal Unstructured Regions Is Important for Transfer of Activated UFM1 to UFC1
Ubiquitin fold modifier 1 (UFM1) is a member of the ubiquitin-like protein family. UFM1 undergoes a cascade of enzymatic reactions including activation by UBA5 (E1), transfer to UFC1 (E2) and selective conjugation to a number of target proteins via UFL1 (E3) enzymes. Despite the importance of ufmyla...
Autores principales: | Wesch, Nicole, Löhr, Frank, Rogova, Natalia, Dötsch, Volker, Rogov, Vladimir V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8304084/ https://www.ncbi.nlm.nih.gov/pubmed/34299007 http://dx.doi.org/10.3390/ijms22147390 |
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