IGF-1 Haploinsufficiency Causes Age-Related Chronic Cochlear Inflammation and Increases Noise-Induced Hearing Loss

Insulin-like growth factor 1 (IGF-1) deficiency is an ultrarare syndromic human sensorineural deafness. Accordingly, IGF-1 is essential for the postnatal maturation of the cochlea and the correct wiring of hearing in mice. Less severe decreases in human IGF-1 levels have been associated with other h...

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Detalles Bibliográficos
Autores principales: Celaya, Adelaida M., Rodríguez-de la Rosa, Lourdes, Bermúdez-Muñoz, Jose M., Zubeldia, José M., Romá-Mateo, Carlos, Avendaño, Carlos, Pallardó, Federico V., Varela-Nieto, Isabel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8304185/
https://www.ncbi.nlm.nih.gov/pubmed/34359856
http://dx.doi.org/10.3390/cells10071686

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8304185/
https://www.ncbi.nlm.nih.gov/pubmed/34359856
http://dx.doi.org/10.3390/cells10071686

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