Cargando…
IGF-1 Haploinsufficiency Causes Age-Related Chronic Cochlear Inflammation and Increases Noise-Induced Hearing Loss
Insulin-like growth factor 1 (IGF-1) deficiency is an ultrarare syndromic human sensorineural deafness. Accordingly, IGF-1 is essential for the postnatal maturation of the cochlea and the correct wiring of hearing in mice. Less severe decreases in human IGF-1 levels have been associated with other h...
Autores principales: | Celaya, Adelaida M., Rodríguez-de la Rosa, Lourdes, Bermúdez-Muñoz, Jose M., Zubeldia, José M., Romá-Mateo, Carlos, Avendaño, Carlos, Pallardó, Federico V., Varela-Nieto, Isabel |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8304185/ https://www.ncbi.nlm.nih.gov/pubmed/34359856 http://dx.doi.org/10.3390/cells10071686 |
Ejemplares similares
-
G6PD overexpression protects from oxidative stress and age‐related hearing loss
por: Bermúdez‐Muñoz, Jose M., et al.
Publicado: (2020) -
Transforming growth factor β1 inhibition protects from noise-induced hearing loss
por: Murillo-Cuesta, Silvia, et al.
Publicado: (2015) -
Corrigendum: Transforming growth factor β1 inhibition protects from noise-induced hearing loss
por: Murillo-Cuesta, Silvia, et al.
Publicado: (2015) -
Therapeutic efficiency of the APAF‐1 antagonist LPT99 in a rat model of cisplatin‐induced hearing loss
por: Murillo‐Cuesta, Silvia, et al.
Publicado: (2021) -
Deficit of mitogen-activated protein kinase phosphatase 1 (DUSP1) accelerates progressive hearing loss
por: Celaya, Adelaida M, et al.
Publicado: (2019)