New In Vitro-In Silico Approach for the Prediction of In Vivo Performance of Drug Combinations

Pharmacokinetic (PK) studies improve the design of dosing regimens in preclinical and clinical settings. In complex diseases like cancer, single-agent approaches are often insufficient for an effective treatment, and drug combination therapies can be implemented. In this work, in silico PK models we...

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Detalles Bibliográficos
Autores principales: Correia, Cristiana, Ferreira, Abigail, Santos, Joana, Lapa, Rui, Yliperttula, Marjo, Urtti, Arto, Vale, Nuno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8304213/
https://www.ncbi.nlm.nih.gov/pubmed/34299532
http://dx.doi.org/10.3390/molecules26144257

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8304213/
https://www.ncbi.nlm.nih.gov/pubmed/34299532
http://dx.doi.org/10.3390/molecules26144257

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